| Aegean Airlines | Athens |
| Aeroflot | Moscow–Sheremetyevo |
| Afriqiyah Airways | Benghazi, Misrata, Tripoli–Mitiga |
| Air Algérie | Algiers |
| Air Arabia | Abu Dhabi, Al Jawf, Bahrain, Bergamo, Dammam, Gassim, Ha’il, Hurghada, Jeddah, Khartoum, Luxor, Marseille, Muscat, Ras Al Khaimah, Riyadh, Sharjah, Tabuk, Ta’if, Yanbu Seasonal: Aswan |
| Air Cairo | Abha, Abu Simbel, Aswan, Bilbao, Bologna, Catania, Dakar–Diass (begins 1 December 2023), Gassim, Hurghada,Jeddah, Kuwait City, Luxor, Málaga, Marsa Alam, Milan–Malpensa, Ouagadougou (begins 1 December 2023), Riyadh, Rome–Fiumicino, Sharm El Sheikh, Sohag, Tangier, Valencia Seasonal: Marsa Matruh |
| Air Canada | Seasonal: Montréal–Trudeau |
| Air France | Paris–Charles de Gaulle |
| Air Montenegro | Seasonal charter: Podgorica |
| Air Serbia | Belgrade |
| Alexandria Airlines | Jeddah |
| AlMasria Universal Airlines | Seasonal: Bergamo, Kuwait |
| Austrian Airlines | Vienna |
| Azur Air | Seasonal charter: Kazan, Krasnodar, Novosibirsk, Samara, Tyumen, Ufa, Yekaterinburg |
| Badr Airlines | Khartoum |
| BH Air | Seasonal charter: Sofia |
| British Airways | London–Heathrow |
| China Eastern Airlines | Shanghai–Pudong (begins 11 December 2023 |
| Cyprus Airways | Seasonal: Larnaca |
| Egyptair | Abha, Abu Dhabi, Abuja, Accra, Addis Ababa, Alexandria, Algiers, Amman–Queen Alia, Amsterdam, Asmara, Assiut, Aswan, Athens, Baghdad, Bahrain, Barcelona, Beijing–Capital, Beirut, Benghazi,Berlin, Brussels, Budapest, Casablanca, Copenhagen, Dammam, Dar es Salaam, Delhi, Dhaka, Doha, Douala, Dubai–International, Dublin, Düsseldorf, El Kharga, Entebbe, Erbil, Frankfurt, Gassim, Geneva, Guangzhou, Hangzhou, Hurghada, Istanbul,Jakarta–Soekarno-Hatta, Jeddah, Johannesburg–O.R. Tambo, Juba, Kano, Khartoum, Kigali, Kinshasa–N’djili, Kuwait City, Lagos, Larnaca, London–Heathrow, Luxor, Madrid, Manchester, Marsa Alam, Medina, Milan–Malpensa, Misrata, Moroni, Moscow–Domodedovo,Mumbai, Munich, Muscat, Nairobi–Jomo Kenyatta, N’Djamena, Newark,New York–JFK, Paris–Charles de Gaulle, Port Sudan, Riyadh, Rome–Fiumicino, Shanghai–Pudong, Sharjah, Sharm El Sheikh, Sohag, Tel Aviv, Tokyo–Narita, Toronto–Pearson, Tripoli–Mitiga, Tunis, Vienna, Lisbon airport, Washington–Dulles Charter: Taba Seasonal charter: Osaka–Kansai, São Paulo–Guarulhos |
| Emirates | Dubai–International |
| Eritrean Airlines | Asmara, Khartoum, Milan–Malpensa |
| Ethiopian Airlines | Addis Ababa |
| Etihad Airways | Abu Dhabi |
| European Air Charter | Seasonal charter: Sofia |
| Flyadeal | Dammam, Jeddah, Riyadh |
| FlyBaghdad | Najaf |
| FlyEgypt | Jeddah, Riyadh, Sharjah |
| Flynas | Abha, Dammam, Jeddah, Medina, Riyadh |
| Gulf Air | Bahrain |
| Iberia | Seasonal: Madrid |
| Iraqi Airways | Baghdad, Basra, Erbil, Sulaimaniyah |
| ITA Airways | Rome–Fiumicino |
| Jazeera Airways | Kuwait City |
| Jordan Aviation | Amman–Queen Alia |
| Kuwait Airways | Kuwait City |
| Libyan Airlines | Benghazi, Tripoli–Mitiga |
| LOT Polish Airlines | Warsaw–Chopin |
| Lufthansa | Frankfurt, Munich |
| Middle East Airlines | Beirut |
| Neos | Milan–Malpensa |
| Nesma Airlines | Abha, Gassim, Jeddah, Kuwait City, Tabuk, Ta’if, Yanbu |
| Nile Air | Abha, Al Ain, Al Jawf, Aswan, Baghdad, Basra, Düsseldorf,Gassim, Ha’il, Hofuf, Hurghada, Istanbul–Sabiha Gökçen, Jeddah, Jizan, Kuwait, Luxor, Port Sudan, Rome–Fiumicino, Sharm El Sheikh, Sohag, Stockholm–Arlanda, Tabuk, Ta’if, Yanbu |
| Nordwind Airlines | Saint Petersburg |
| Oman Air | Muscat |
| Petroleum Air Services | Seasonal Charter: Abu Rudeis, Alexandria, Antalya, Aqaba, Aswan, El Kharga, Hurghada, Luxor, Paphos, Sharm El Sheikh |
| Qatar Airways | Doha |
| Rossiya Airlines | Sochi |
| Royal Air Maroc | Casablanca |
| Royal Jordanian | Amman–Queen Alia |
| Saudia | Abha, Jeddah, Medina, Riyadh |
| Sichuan Airlines | Beijing–Capital, Chengdu–Tianfu |
| Smartwings | Prague |
| Sudan Airways | Khartoum, Port Sudan |
| Swiss International Air Lines | Zürich |
| Syrian Air | Damascus, Latakia |
| Tarco Aviation | Khartoum |
| TAROM | Bucharest–Otopeni |
| Transavia | Paris–Orly |
| Tunisair | Tunis |
| Turkish Airlines | Istanbul |
| Vueling | Barcelona airport , Paris–Orly |
| Yemenia | Aden, Seiyun |
